High-quality Comprehensive Clinical Research Services

Are you a potential Sponsor?

Medical breakthroClinical Research Professionalsughs result from years of research into diseases and potential treatment options. For the past 14 years, Dr. Margherita has led or assisted with research for universities, government agencies, and the private sector. Most recently, he has served as a Principle Investigator for Clinical Research Professionals (clinicalresearchprofessionals.net), a comprehensive clinical research company providing professional, high quality comprehensive clinical research services.

Dr. Margherita participates in Phase II, III and IV trials in a wide range of medical conditions including back pain, diabetic neuropathy, and arthritis. These studies help to determine: (1) how a drug compares with other drugs already in the market; (2) a drug’s long-term effectiveness and impact on a patient’s quality of life; and (3) the cost-effectiveness of a drug therapy relative to other traditional and new therapies.

Clinical Research Professionals and Dr. Margherita have established a Medical Partners Program to assist medical practices in identifying potentially appropriate patient for clinical trials. This program allows the practicing physician to be an integral part of the research process with communication of your patient’s enrollment, any clinically significant laboratory values that warrant treatment, and any medical issues that arise during a trial. Medical Partners are provided assistance and financial remuneration for the identification of appropriate candidates in specific disease states. The amount of remuneration varies for each study.

If your medical practice is interested in becoming a Medical Partner, please contact Dr. Margherita of Clinical Research Professionals at 636-220-1200.

Are You Interested In Participating?

Medical breakthroughs result from years of research into diseases and potential treatment options. For the past 14 years, Dr. Margherita has led or assisted with research for universities, government agencies, and the private sector. Most recently, he has served as a Principle Investigator for Clinical Research Professionals (clinicalresearchprofessionals.net), a comprehensive clinical research company providing professional, high quality comprehensive clinical research services.

Clinical trials, also known as clinical studies, test potential treatments in human volunteers to see if they should be approved for wider use in the general population. A treatment could be a drug, medical device, or biologic, such as a vaccine, blood product, or gene therapy. An agent is first tested in laboratory animals to determine potential toxicity before it can be tried in people. Treatments having acceptable safety profiles and showing the most promise are then moved into clinical trials.

Clinical Trials

Clinical trials enroll people who are alike in certain ways depending on the study’s purpose. Every protocol identifies some specific characteristics that the people should have in order to participate in the study. They may include the type of disease and its stage, age and general health. In 2002, more than a million individuals participated in 80,000 clinical trials in the United States, most sponsored by pharmaceutical manufacturers. Clinical trials are critical for screening new drugs and determining their effectiveness. Many individuals enroll in clinical trials in order to get access to new medications that are not yet available in the US. The clinical testing of experimental medications or devices is normally done in three phases. Phase I studies are usually the first phase of safety testing and usually require several hours of monitoring or an overnight stay. Once a drug has been shown to be safe, it must be tested for effectiveness. This second phase of testing (called “phase II” studies) may last from several months to two years, and involve up to several hundred patients. In a phase III study, a drug is tested in several hundred to several thousand patients. This large-scale testing provides the pharmaceutical company and the FDA with a more thorough understanding of the drug’s effectiveness, benefits, and the range of possible adverse reactions. In some cases, a Phase IV trial is done after a medication is released to monitor its effectiveness or to identify new conditions potentially benefited by the drug.

Dr. Margherita participates in Phase II, III and IV trials in a wide range of medical conditions such as back pain, diabetic neuropathy, and arthritis. These studies help to determine: (1) how a drug compares with other drugs already in the market; (2) a drug’s long-term effectiveness and impact on a patient’s quality of life; and (3) the cost-effectiveness of a drug therapy relative to other traditional and new therapies.

Participating in clinical trials offers many opportunities to learn more about treatments and disease. However, it is important to have a good understanding of the risks and benefits of any study when making a decision to participate.

If you are interested in participating in ongoing or future studies, please feel free to contact either Dr. Magherita’s staff or Clinical Research Professionals at 636-220-1200.

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Diana in Florissant, MO

Dr. Margherita has been able to successfully treat my aches and pains over the years. He listens well, diagnoses correctly and treats with overwhelming success.

Diana in Florissant, MO
Vanessa in Chesterfield, MO

I have been recommending Dr. Margherita since my first appointment & experience with his expertise at diagnosis. He is the best, Doctor.

Vanessa in Chesterfield, MO

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